is a concept introduced by Chilean biologists Humberto Maturana and Francisco Varela in the 1970s to describe systems that maintain and reproduce themselves through internal processes. Literally meaning "self-creation" or "self-production," an autopoietic system is defined as a network of processes that continuously generate and realize the components that produce them, thereby sustaining the system’s identity and boundaries.

Core Characteristics

  • Self-Production: The system produces its own components (e.g., a cell produces enzymes and membranes that maintain its structure).

  • Operational Closure: The system operates based on its own internal logic and codes, not dependent on external inputs for its core functioning.

  • Structural Coupling: While operationally closed, the system interacts with its environment through selective responses, adapting over time through repeated interactions.

  • Distinction from Allopoiesis: Unlike allopoietic systems (e.g., a car factory, which produces something other than itself), autopoietic systems produce themselves.

Key Examples

  • Biological Cells: The eukaryotic cell is a canonical example—its metabolic processes generate the proteins, membranes, and organelles that sustain it.

  • Social Systems: Niklas Luhmann extended the concept to sociology, describing society as a network of self-reproducing communications, where legal, economic, and educational systems operate autonomously based on internal codes (e.g., legal/illegal, profitable/unprofitable).

  • Conversations and Institutions: A conversation persists not because of fixed content, but through continuous mutual responses; social norms endure because people repeatedly enact them.

Broader Applications

  • Cognition: Maturana and Varela argued that cognition is an autopoietic process—understanding arises from internal neural networks, not direct perception of reality.

  • Ecology: Autopoietic Ecology views ecosystems, institutions, and even digital platforms as dynamic, self-sustaining processes rather than static entities.

  • AI and Systems Theory: The concept informs models of self-organizing systems, including artificial intelligence, where systems evolve through recursive internal processes.

Philosophical Implications

Autopoiesis challenges the idea of fixed essences or external control. It suggests that stability is an active, ongoing achievement—systems persist by continuously regenerating their own operations. This perspective fosters a new ethics of co-existence, emphasizing careful perturbation to support self-renewal rather than domination.

In short: Autopoiesis is a framework for understanding living and complex systems not as static objects, but as dynamic, self-maintaining processes that define themselves through their own operations.

AI-generated answer. Please verify critical facts.
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Wikipedia
en.wikipedia.org â€ē wiki â€ē Autopoiesis
Autopoiesis - Wikipedia
December 9, 2025 - The term autopoiesis (from Greek ÎąáŊĪ„o- (auto) 'self' and Ī€ÎŋÎ¯ÎˇĪƒÎšĪ‚ (poiesis) 'creation, production'), one of several current theories of life, refers to a system capable of producing and maintaining itself by creating its own parts. The term was introduced in the 1972 publication ...
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ScienceDirect
sciencedirect.com â€ē topics â€ē social-sciences â€ē autopoiesis
Autopoiesis - an overview | ScienceDirect Topics
Autopoiesis, or ‘self-production,’ ... nonliving. An autopoietic system was defined as a network of inter-related component-producing processes such that the components in interaction generate the same network that produced them....
Discussions

Autopoiesis
Who are you? You are that which transforms what you are." — Jordan B Peterson More on reddit.com
🌐 r/DrJohnVervaeke
4
7
February 12, 2021
Life as an autopoietic system - Attempt of a structure-realistic elucidation - Part 2

I look into this a lot in my personal time. It'd be fun to talk.

Many programs that emphasize psychological treatment of severe psychological dysfunction utilize cognitive restructuring methods for alleviation of symptoms. What are your thoughts about internal organization as a utility for the alleviation of psychological disorder?

How about teaching internal structuring to redirect maladaptive thought patterns and behaviors? What methodologies have you found to be effective either personally or within research?

Is a structural approach applicable enough to explain more than human biology? Structures are limited by the system in which they operate, which system are all structures limited by and how do you find those structures to be limited? Can we develop structures which transcend sentience?

My favorite question right now: Can the systems involved in the physicality of the universe and those more abstract psychological systems within the mind be compared effectively with a single set of structures? (I believe yes and that the systems are quite relatable)

I love extrapolating systems and implementing them into programs and approaches!

More on reddit.com
🌐 r/Metaphysics
1
3
April 7, 2020
Autopoiesis and Humanism
Based on how you frame your question, I would say that autopoeisis does preclude humanism, in the sense that post-humanism has sought to bracket and/or question the presumption of individual agency/autonomy of human beings, in order to see how it is antecedently suspended in relational systems or milieus that feed back upon an individual, by various means. Autopoeitic theory is based in second-order cybernetics, which is (quoting from first line of the Wikipedia entry) where "the role of the observer is appreciated and acknowledged rather than disguised, as had become traditional in western science". This is the epistemological/methodological stance of autopoesis, and it helps frame one of its central questions, which is something like: what makes up the relational difference between the physical individuation of matter, the vital individuation of living things, and the collective individuation of a member of a social population? In material below from Maturana and Varela, biologically it amounts to the production of some membrane between inside and outside, where the exterior milieu or environment of a living thing is met and transformed into a principle and set of dynamics for it to continue living, through its auto-organization. From here people have analogized the basic biological account over into social systems and technology, as you'll see from some of the references below. Self-organization would seem to suggest autonomy as you put it above, but I think it's more about digging in to the underlying principles of self-regulation in a given milieu that go into any sense of an individual's autonomy. Again, Maturana and Varela write that "...the living organization can only by characterized unambiguously by specifying the network of interactions of components which constitute a living system as a whole, that is, as a 'unity'" In terms of how autopoeisis has traveled into the (post-)humanities, there were some early connections in Heidegger's Being and Time discussing our phenomenological relationship to signs in a context, which made reference to the work of Jakob von Uexkull, a German biologist who developed the precursor notion of an animal's Umwelt -- how mind interprets world for a given organism. Geoffrey Winthrop-Young's Afterword in a reprint of von Uexkull's work (noted below) is a good read for how his ideas fit together with the modern humanities context, from Heidegger onwards. At this point I'm waving my hand in a bit of a broad sweep, but basically Von Uexkull and second-order cybernetics found their way into the humanities through certain connections between it and post-structural critiques of meaning. Both are about reflexively characterizing the question of meaning by examining the (historical, embodied, structural) conditions of meaning's construction and closure, for humans and animals alike. Of course there are many, many ways in which this reflexivity of the subject in a 'conditioned milieu' has played out (eg. through appeals to language's paradox of closure via Derridean diffÊrance, through knowledge systems, ideology theory, the unconscious, affect theory, the role of media technologies...) But sticking strictly to autopoeisis and second-order cybernetics, you've already mentioned Niklas Luhmann, so I'll just mention a few more books that have been helpful for me to situate self-organization in this post-humanities context: The reprint of Von Uexkull's treatise (with the afterword), A Foray into the Worlds of Animals and Humans with A Theory of Meaning William Rasch's book Niklas Luhmann's Modernity: The Paradoxes of Differentiation Clarke and Hansen's book Emergence and Embodiment: New Essays on Second-Order Systems Theory Maturana and Varela's book Autopoeisis and Cognition N. Katherine Hayles's book How We Became Posthuman Bernhard Siegert's book Cultural Techniques Henri Atlan's Selected Writings Conversations with Heinz von Foerster in the book The Beginning of Heaven and Earth Has No Name Hope this helps situate you to keep going with your explorations. More on reddit.com
🌐 r/askphilosophy
2
1
June 3, 2022
The autopoiesis of function systems in the movie "Don't look up" - a Luhmannian perspective
Every time I hear about him the more I want to read Luhmann's work. I can't comment on your analysis but it is interesting. More on reddit.com
🌐 r/sociology
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March 23, 2024
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Merriam-Webster
merriam-webster.com â€ē dictionary â€ē autopoiesis
AUTOPOIESIS Definition & Meaning - Merriam-Webster
The meaning of AUTOPOIESIS is the property of a living system (such as a bacterial cell or a multicellular organism) that allows it to maintain and renew itself by regulating its composition and conserving its boundaries.
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Newmaterialism
newmaterialism.eu â€ē almanac â€ē a â€ē autopoietic-system.html
Autopoietic System - New Materialism
An autopoietic system is a system that produces and reproduces its own elements as well as its own structures (Luhmann, 2012, p. 32). The concept was introduced by Chilean biologists Humberto Maturana and Francisco Varela to describe the nature of living systems in general and the organic cell ...
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PubMed
pubmed.ncbi.nlm.nih.gov â€ē 23054553
Autopoiesis 40 years later. A review and a reformulation - PubMed
The concept of autopoiesis was proposed 40 years ago as a definition of a living being, with the aim of providing a unifying concept for biology. The concept has also been extended to the theory of knowledge and to different areas of the social and behavioral sciences.
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Mannaz -
mannaz.com â€ē home â€ē understanding autopoiesis: life, systems, and self-organisation
Understanding Autopoiesis: Life, Systems, and Self-Organisation
December 6, 2024 - According to Maturana and Varela, a living organism is a network of molecular exchanges that continuously interacts with its environment while maintaining its identity. In an autopoietic system, components are both products of the system and contribute to its ongoing existence.
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Political Theology Network
politicaltheology.com â€ē autopoiesis
Autopoiesis | Political Theology Network
March 1, 2022 - The term designated for them a ... of component parts. Generally speaking, an autopoietic system is one that generates and reproduces itself through itself....
Find elsewhere
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UBC Blogs
blogs.ubc.ca â€ē etec531dbang â€ē 2011 â€ē 07 â€ē 12 â€ē autopoieticself-creating-and-allopoieticproducing-something-other-than-themselves
Autopoietic=Self-creating and Allopoietic=producing something other than themselves – Diana Bang's ETEC 531 e-portfolio
Autopoietic are self-operating and self-contained. For example, living organisms are autopoietic in the sense that they can be born and die on their own. In contrast, allopoietic processes depend on aspects outside of themselves in order for their survival. According to Guattari (1995) there ...
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Critical Legal Thinking
criticallegalthinking.com â€ē home â€ē niklas luhmann: what is autopoiesis?
Niklas Luhmann: What is Autopoiesis?
February 28, 2022 - An autopoietic system produces itself while simultaneously producing its own conditions, both internal and external.
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Cambridge EdgeLab
cambridgeedgelab.org â€ē autopoietic-ecology
Autopoietic Ecology – Cambridge EdgeLab
August 29, 2025 - The word autopoietic means “self-making.” Instead of assuming that systems exist because of some hidden essence or fixed foundation, autopoietic ecology shows that they persist by continuously regenerating the very operations that allow ...
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Reddit
reddit.com â€ē r/drjohnvervaeke â€ē autopoiesis
r/DrJohnVervaeke on Reddit: Autopoiesis
February 12, 2021 -

I’m reading a book that covers the idea of autopoiesis—a form of dynamic self-organization, a term that Vervaeke uses in his Awakening from the Meaning Crisis lectures, more so towards the end of the series. I’m noticing that the author keeps coming back to a definition of autopoiesis. Here are a few.

  • [Autopoietic systems,] through their interactions generate and participate recusively in the same network of reactions which produced them.

  • â€Ļ [they’re] organized in such a way that [its] constituent processes produce the components necessary for the continuance of those same processes.

  • The reaction network which characterizes the organization of the system must produce all the species of molecular components which are considered to materially contitute the system, and these components must themselves generate the reaction network.

  • Every molecular reaction in the system is generated by the very same system that these molecular reactions produce.

  • (i) The system must have a semipermeable boundary; (ii) the boundary must be produced by a network of reactions that takes place within the boundary; and (iii) the network of reactions must include reactions that regenerate the components of the system.

  • Metabolic processes within the cell determine these boundaries, but the metabolic processes themselves are made possible by those very boundaries.

  • Such spontaneous pattern formation is exactly what we mean by self-organization: the system organizes itself, but there is no ‘self’, no agent inside the system doing the organizing.

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Medium
medium.com â€ē @apeironkosmos â€ē autopoietic-systems-exploring-the-self-organizing-nature-of-life-f81f197342a8
Autopoietic Systems~ Exploring the Self-Organizing Nature of Life | by ~~~Shapeshifter32~~~ | Medium
July 14, 2024 - ~~~~~At its core, autopoiesis posits that living organisms are not merely passive recipients of external stimuli but actively engage in shaping their own identity and maintaining their integrity. Consider the human body – a complex autopoietic system where cells collaborate, regenerate, and adapt, ensuring the perpetual renewal of tissues and organs.
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Wiktionary
en.wiktionary.org â€ē wiki â€ē autopoietic
autopoietic - Wiktionary, the free dictionary
If living systems are machines, that they are physical autopoietic machines is trivially obvious: they transform matter into themselves in a manner such that the product of their operation is their own organization.
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Oxford Reference
oxfordreference.com â€ē display â€ē 10.1093 â€ē oi â€ē authority.20110803095436328
Autopoiesis - Oxford Reference
Self creation or self organization. The term was introduced by the evolutionary biologists Humberto Maturana and Francisco Varela in their groundbreaking book, Autopoiesis and Cognition: The Realization of the Living (1972).
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Boston University Law School
scholarship.law.bu.edu â€ē faculty_scholarship â€ē 140
"Niklas Luhmann's Theory of Autopoietic Legal Systems" by Hugh Baxter
Between 1984 and his death in 1998, German sociologist Niklas Luhmann developed a comprehensive theory of what he called autopoietic or self-referential systems.He worked out this approach both at the level of a social system as a whole and at the level of various social subsystems, such as state, economy, science, religion, education, art, family, and — the concern of the present article — law.
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Amazon
amazon.com â€ē Autopoiesis-Cognition-Realization-Studies-Philosophy â€ē dp â€ē 9027710163
Amazon.com: Autopoiesis and Cognition: The Realization of the Living (Boston Studies in the Philosophy of Science, Vol. 42): 9789027710161: Maturana, H.R., Varela, F.J.: Books
Amazon.com: Autopoiesis and Cognition: The Realization of the Living (Boston Studies in the Philosophy of Science, Vol. 42): 9789027710161: Maturana, H.R., Varela, F.J.: Books
Amazon.com: Autopoiesis and Cognition: The Realization of the Living (Boston Studies in the Philosophy of Science, Vol. 42): 9789027710161: Maturana, H.R., Varela, F.J.: Books
Price   $119.99
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PhilArchive
philarchive.org â€ē archive â€ē BICSA pdf
Systems, Autopoietic
autopoietic approach belongs to a systemic tradition
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ScienceDirect
sciencedirect.com â€ē topics â€ē computer-science â€ē autopoietic-system
Autopoietic System - an overview | ScienceDirect Topics
An autopoietic system is a network of inter-related component-producing processes that generate the same network that produced them. It is a concept introduced to differentiate living systems from non-living systems.
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Quora
quora.com â€ē What-is-autopoiesis-in-terms-of-psychological-systems-theory-and-what-would-a-practical-example-of-this-be
What is autopoiesis in terms of psychological systems theory and what would a practical example of this be? - Quora
Answer (1 of 2): The Chilean scientist Humberto Maturana (along with Francisco Varela) developed the notion of autopoiesis to describe the workings of the human nervous system â€Ļ so it would be correct to say autopoiesis IS part of psychological systems theory.